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. 2021 Jun 11;38(7):4013–4025. doi: 10.1007/s12325-021-01799-3

Table 1.

Main general characteristics according to ACEi-based or ARB-based triple therapy

All study population (n = 520) Patients taking ACEi-based triple therapy (n = 189) Patients taking ARB-based triple therapy (n = 331) p*
Age (years) 62.7 ± 12.2 62.4 ± 11.8 62.8 ± 12.3 0.728
Sex (male) 61.7% 64.6% 60.1% 0.318
BMI (kg/m2) 28.4 ± 4.4 28.2 ± 4.3 28.6 ± 4.4 0.329
Smoking habit 51.3% 50.8% 51.7% 0.849
T2DM 25.4% 29.9% 22.8% 0.073
eGFR (ml/min/1.73 m2) 77.1 ± 22.8 77.7 ± 22.3 76.8 ± 23.1 0.660
Number of antihypertensive pills
 1 8.1% 22.2% 0.0%
 2 87.3% 77.2% 93.1% < 0.001
 3 4.6% 0.5% 6.9%
ATI 5.49 ± 0.37 5.44 ± 0.40 5.52 ± 0.36 0.017
Use of concomitant medications 61.3% 58.5% 62.7% 0.429

*Comparison between patients taking ACEi-based triple therapy vs patients taking ARB-based triple therapy

ACEi angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, BMI body mass index, T2DM type 2 diabetes mellitus, eGFR estimated glomerular filtration rate, ATI antihypertensive treatment intensity