We investigated the prevalence and predictors of ambulatory blood pressure control in patients with essential hypertension taking a triple antihypertensive therapy (renin–angiotensin system inhibitor + calcium channel blocker + thiazide/thiazide-like diuretic, in either free or fixed-dose combinations)

Patients taking a triple-therapy with ACE inhibitors had a higher prevalence of both 24-h and daytime blood pressure control than patients taking a triple-therapy with angiotensin receptor blockers at univariate analysis

This association was lost after taking into account the number of antihypertensive pills taken in the multivariate analysis: the lower the number of pills, the higher the prevalence of ambulatory blood pressure control