Table 2.

Course of disease

	Cohort n = 81 (%)	MGMT positive n = 31 (%)	MGMT negative n = 50 (%)
Treatment response (TR) n = 23
Complete remission (CR)	2 (8.7)	2 (12.5)	0 (0)
Partial remission (PR)	2 (8.7)	1 (6.3)	1 (14.3)
Stable disease (SD)	19 (82.6)	13 (81.2)	6 (85.7)
Progressive disease (PD) n = 58
RANO-criteria	24 (41.4)	5 (33.3)	19 (44.2)
18F-FET-PET	9 (15.5)	9 (6.7)	8 (18.6)
Surgery	25 (43.1)	25 (43.1)	16 (37.2)

Treatment response dependent from MGMT methylation status, and diagnosis of progressive disease