Table 2.
Sensitivity and specificity of DT predictions according to fiber tract
| Tract | TP | TN | FP | FN | Exclusions | Sensitivity (%) | Specificity | Accuracy (%) | EARLY DEFICITa |
|---|---|---|---|---|---|---|---|---|---|
| CST (n = 51) | 32 | 6 | 1 | 0 | 11 | 84.2 | 85.7% | 97.4 | N = 20 |
| Arcuate (n = 29) | 24 | 2 | 0 | 0 | 4 | 92.3 | 100% | 100 | N = 13 |
| IFOF (n = 37) | 33 | 1 | 0 | 1 | 2 | 97.1 | 100% | 97.1 | N = 13 |
| OR (n = 19) | 13 | 0 | 2 | 0 | 4 | 100 | N/A* | 86.7 | N = 4 |
| ILF (n = 7) | 5 | 0 | 1 | 0 | 1 | 100 | N/A* | 83.3 | N = 2 |
Sensitivity, specificity and accuracy of diffusion tractography (DT) predictions for individual fiber tracts
CST corticospinal tract, IFOF inferior fronto-occipital fasciculus, OR optic radiations, ILF inferior longitudinal fasciculus, TP True Positive, TN True Negative, FP False Positive, FN False Negative, N/A Not available
*In the absence of True Negative instances, specificity cannot be meaningfully quantified
aEarly deficit = new or worse deficit emerging during surgery or in the immediate post-surgical period. Almost all deficits were transient, with the very small number (4%) of persisting deficits each involving sensorimotor functions (CST), see “Results” section