Fig. 3.

a The illustration indicates regions of interest (ROIs) used for quantifications of MAP2- and NF-L-related immunofluorescence intensities after 24h of transient and permanent MCAO in mice. b When compared to the contralateral hemisphere, the MAP2-related immunofluorescence intensity was significantly reduced throughout the infarcted cortex, c whereas the increase of NF-L-related immunoreactivity was only significant in ROIs of the somatosensory cortex. Neither MAP2- nor NF-L-related immunofluorescence intensities differed significantly between transient and permanent MCAO. The dashed line represents the infarct border. Sample sizes in b and c: n=6 for all ROIs. Data are presented as mean values; error bars indicate the standard error. *p<0.05, **p<0.01, ***p<0.001