Table 3.
Toxicities of compounds
| Number | Compounds | Mouse NTP | Rat NTP | Ames | DTP | ||
|---|---|---|---|---|---|---|---|
| Female | Male | Female | Male | ||||
| 1 | ZINC000005664046 | 0 | 0.666 | 1 | 0.994 | 0 | 0.004 |
| 2 | ZINC000005922875 | 0 | 0.965 | 1 | 0.991 | 0 | 1 |
| 3 | ZINC000014711612 | 0.926 | 1 | 1 | 0.927 | 1 | 0.989 |
| 4 | ZINC000003978135 | 0.024 | 1 | 0 | 1 | 0 | 0 |
| 5 | ZINC000003978134 | 0 | 1 | 1 | 1 | 0 | 0.001 |
| 6 | ZINC000013451339 | 0 | 0.943 | 0 | 0.038 | 0 | 1 |
| 7 | ZINC000002008850 | 0.246 | 1 | 0.999 | 0.038 | 1 | 0.974 |
| 8 | ZINC000028520217 | 0 | 1 | 0 | 0.415 | 0 | 0.998 |
| 9 | ZINC000003951623 | 0 | 0.999 | 1 | 0.023 | 0 | 0.824 |
| 10 | ZINC000004175510 | 0 | 1 | 1 | 1 | 0 | 0.001 |
| 11 | ZINC000072320087 | 0 | 1 | 1 | 0.995 | 0 | 1 |
| 12 | ZINC000031494940 | 1 | 0 | 0 | 0.053 | 0 | 1 |
| 13 | ZINC000001702730 | 0 | 1 | 1 | 1 | 0 | 0.99 |
| 14 | ZINC000039066223 | 0.001 | 1 | 1 | 0.288 | 1 | 1 |
| 15 | ZINC000004098005 | 0 | 1 | 1 | 0.001 | 1 | 1 |
| 16 | ZINC000002525131 | 0 | 1 | 1 | 1 | 0 | 1 |
| 17 | ZINC000013298233 | 0.024 | 1 | 0 | 1 | 0 | 0 |
| 18 | ZINC000026489484 | 0.011 | 0.006 | 0.102 | 0.989 | 0 | 1 |
| 19 | ZINC000005854691 | 0 | 1 | 1 | 0.001 | 1 | 1 |
| 20 | ZINC000005670074 | 0.035 | 0 | 0.996 | 0.564 | 0 | 1 |
| 21 | Obatoclax | 1 | 0.028 | 1 | 0.858 | 1 | 0.982 |
| 22 | Venetoclax | 1 | 1 | 1 | 0.998 | 0 | 0 |
NTP < 0.3(noncarcinogen); > 0.8(carcinogen)
Ames < 0.3(nonmutagen); > 0.8(mutagen)
DTP < 0.3(nontoxic); > 0.8(toxic)
NTP U.S. National Toxicology Program; DTP developmentaltoxicitypotential