Skip to main content
. 2021 Jul 14;38(8):94. doi: 10.1007/s12032-021-01513-x

Table 3.

Toxicities of compounds

Number Compounds Mouse NTP Rat NTP Ames DTP
Female Male Female Male
1 ZINC000005664046 0 0.666 1 0.994 0 0.004
2 ZINC000005922875 0 0.965 1 0.991 0 1
3 ZINC000014711612 0.926 1 1 0.927 1 0.989
4 ZINC000003978135 0.024 1 0 1 0 0
5 ZINC000003978134 0 1 1 1 0 0.001
6 ZINC000013451339 0 0.943 0 0.038 0 1
7 ZINC000002008850 0.246 1 0.999 0.038 1 0.974
8 ZINC000028520217 0 1 0 0.415 0 0.998
9 ZINC000003951623 0 0.999 1 0.023 0 0.824
10 ZINC000004175510 0 1 1 1 0 0.001
11 ZINC000072320087 0 1 1 0.995 0 1
12 ZINC000031494940 1 0 0 0.053 0 1
13 ZINC000001702730 0 1 1 1 0 0.99
14 ZINC000039066223 0.001 1 1 0.288 1 1
15 ZINC000004098005 0 1 1 0.001 1 1
16 ZINC000002525131 0 1 1 1 0 1
17 ZINC000013298233 0.024 1 0 1 0 0
18 ZINC000026489484 0.011 0.006 0.102 0.989 0 1
19 ZINC000005854691 0 1 1 0.001 1 1
20 ZINC000005670074 0.035 0 0.996 0.564 0 1
21 Obatoclax 1 0.028 1 0.858 1 0.982
22 Venetoclax 1 1 1 0.998 0 0

NTP < 0.3(noncarcinogen); > 0.8(carcinogen)

Ames < 0.3(nonmutagen); > 0.8(mutagen)

DTP < 0.3(nontoxic); > 0.8(toxic)

NTP U.S. National Toxicology Program; DTP developmentaltoxicitypotential