Table 5.

Hydrogen bond interaction parameters for each compound with BCL2

Receptor	Compound	Donor atom	Receptor atom	Distances (Å)
1g 5m	ZINC000002525131	ILE14:HN	ASP10:O	1.74
		HIS186:HN	LEU181:O	2.36
		HIS186:HD1	ASN182:OD1	2.1
		ILE189:HN	LEU185:O	1.68
		ILE189:HN	HIS186:O	2.56
		GLN190:HN	HIS186:O	2.26
		GLN190:HE21	HIS186:NE2	2.45
		GLY194:HN	ILE189:O	1.73
		TRP195:HN	ZINC000002525131:O18	2.41
		ZINC000002525131:H47	ASN182:OD1	2
		ZINC000002525131:H49	ZINC000002525131:O18	1.84
		ZINC000002525131:H52	GLN190:OE1	2.3
		ZINC000002525131:H52	ZINC000002525131:O28	1.93
		GLY194:HA1	ILE189:O	2.65
		TRP195:HD1	ZINC000002525131:O18	3.03
	ZINC000013298233	THR7:HN	ZINC000013298233:O14	1.59
		TYR9:HN	ZINC000013298233:O23	2.1
		ASP10:HN	ZINC000013298233:O23	2.84
		ASN11:HN	ZINC000013298233:O23	2.28
		ILE14:HN	ASP10:O	1.74
		HIS186:HN	LEU181:O	2.36
		HIS186:HD1	ASN182:OD1	2.1
		HIS186:HD1	ZINC000013298233:O29	2.31
		ILE189:HN	LEU185:O	1.68
		ILE189:HN	HIS186:O	2.59
		GLN190:HN	HIS186:O	2.26
		GLN190:HE21	HIS186:NE2	2.45
		GLY194:HN	ILE189:O	1.73
		ARG6:HA	ZINC000013298233:O14	2.7
		THR7:HB	ARG6:O	2.25
		GLY8:HA1	ZINC000013298233:O19	2.94
		GLY194:HA1	ILE189:O	2.65
		ZINC000013298233:H47	ALA4:O	2.83
	Obatoclax	GLY5:HN	HIS3:O	1.95
		ILE14:HN	ASP10:O	1.74
		HIS186:HN	LEU181:O	2.36
		HIS186:HD1	ASN182:OD1	2.1
		ILE189:HN	LEU185:O	1.68
		ILE189:HN	HIS186:O	2.59
		GLN190:HN	HIS186:O	2.26
		GLN190:HE21	HIS186:NE2	2.45
		GLY194:HN	ILE189:O	1.73
		Obatoclax:H36	Obatoclax:N15	2.3
		ARG6:HA	Obatoclax:O2	2.57
		ARG6:HD1	GLY5:O	2.74
		ARG6:HD2	GLY5:O	3.02
		THR7:HB	ARG6:O	2.25
		GLY194:HA1	ILE189:O	2.65
		Obatoclax:H26	GLY5:O	3.04