Fig. 2.

Functional network of novel and known candidate genes. Based on co-expression data from BrainSpan and PPI data from IntAct, 159 candidate genes formed a large interconnected functional network, mainly involving the following major functional clusters: chromatin organization, essential genes, nervous system development, FMRP targets, behavior, and synapse organization. Novel candidate genes are in red circles and known candidate genes are in green circles. Different line types between nodes represent the interactions existing in BrainSpan or IntAct or in both BrainSpan and IntAct