Table 3.

Effects on quality of life and psychological profiles

	SAT (n = 26)			Escitalopram (n = 23)			Pa
	Baseline	After treatment	P	Baseline	After treatment	P
IBS-QOL
Dysphoria	41.44 ± 6.53	25.59 ± 6.20	0.0008	36.81 ± 5.24	24.48 ± 4.06	0.0128	0.722
Interference with activity	38.28 ± 6.56	24.77 ± 5.47	0.0011	34.52 ± 4.85	24.80 ± 4.89	0.0503	0.67
Body image	43.75 ± 6.15	27.17 ± 5.81	0.0003	36.11 ± 6.94	26.74 ± 6.53	0.0369	0.3427
Health worry	47.83 ± 6.97	32.61 ± 6.75	0.0038	41.67 ± 6.46	29.63 ± 4.87	0.0205	0.719
Food avoidance	51.81 ± 7.14	37.32 ± 7.1	0.0024	48.61 ± 7.14	41.20 ± 6.34	0.0494	0.265
Social reaction	39.58 ± 6.69	26.81 ± 5.95	0.01	24.65 ± 4.86	20.83 ± 5.3	0.261	0.278
Sexual	33.70 ± 8.11	25.00 ± 7.12	0.0391	35.42 ± 7.65	28.47 ± 7.62	0.3481	0.9672
Relationship	31.52 ± 6.48	14.86 ± 4.71	0.0008	25.46 ± 4.23	15.28 ± 2.72	0.0322	0.3182
SCL-90R
GSI	0.58 ± 0.10	0.42 ± 0.09	0.02	0.46 ± 0.09	0.28 ± 0.04	0.02	0.919
PST	27.58 ± 3.90	21.71 ± 3.35	0.02	25.33 ± 4.1	18.06 ± 2.53	0.0353	0.848
Somatization	0.97 ± 0.14	0.82 ± 0.13	0.37	0.78 ± 0.15	0.50 ± 0.08	0.0375	0.4274
Obsessive-compulsive	0.77 ± 0.15	0.63 ± 0.16	0.127	0.55 ± 0.10	0.32 ± 0.06	0.0062	0.6076
Interpersonal sensitivity	0.47 ± 0.13	0.26 ± 0.09	0.092	0.44 ± 0.13	0.27 ± 0.08	0.109	0.587
Depression	0.73 ± 0.15	0.47 ± 0.14	0.004	0.67 ± 0.15	0.41 ± 0.09	0.019	0.7593
Anxiety	0.48 ± 0.10	0.32 ± 0.08	0.124	0.26 ± 0.09	0.11 ± 0.04	0.083	0.488
Hostility	0.28 ± 0.06	0.18 ± 0.04	0.106	0.19 ± 0.05	0.18 ± 0.04	0.305	0.219
Phobic anxiety	0.29 ± 0.09	0.17 ± 0.08	0.229	0.17 ± 0.06	0.08 ± 0.03	0.124	0.867
Paranoid ideation	0.30 ± 0.11	0.15 ± 0.04	0.167	0.15 ± 0.05	0.10 ± 0.05	0.495	0.577
Psychoticism	0.27 ± 0.08	0.17 ± 0.05	0.392	0.17 ± 0.06	0.08 ± 0.02	0.0734	0.861

Data expressed as mean ± SEM.

CSBM, complete spontaneous bowel movement; GSI, global severity index; IBS-QOL, irritable bowel syndrome quality of life; PSDI, positive symptom distress index; PST, positive symptoms total; SAT, sensory adaptation training.

^aP: SAT vs escitalopram.