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. 2021 Jul 13;3(7):e0467. doi: 10.1097/CCE.0000000000000467

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Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 1. — Plasma interleukin-1 receptor antagonist (IL-1ra) and thrombomodulin levels are significantly higher on days 2 and 3 in patients with a functional decline at hospital discharge. Comparison of plasma biomarker levels in children with and without functional decline at hospital discharge following acute respiratory failure: (A) IL-1ra, (B) thrombomodulin, (C) interleukin-8 (IL-8), (D) plasminogen activator inhibitor-1 (PAI-1). The numbers below each graph represent the number of plasma samples analyzed on each day in those with no decline in functional status and those with worsening of functional status at discharge. *p < 0.05 for comparison of biomarker level in those with and without decline in functional status on the indicated day. IQR = interquartile range.