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. 2021 Apr 19;39(21):2339–2349. doi: 10.1200/JCO.21.00174

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© 2021 by American Society of Clinical Oncology

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FIG 4. — Treatment duration and time to response in (A) patients completing 35 cycles of pembrolizumab treatment and (B) patients who received a second course of pembrolizumab treatment. Light red bars indicate the first course of pembrolizumab treatment duration. Light teal bars indicate the (A) first course follow-up duration or (B) second course of treatment duration. Follow-up was defined as the time to progression or last nonprogression assessment by investigator. Response was assessed by RECIST v1.1 per investigator review. The maximum treatment duration for the second course was 17 cycles. ^aPatient developed a secondary malignancy. CR, complete response; NE, nonevaluable; PD, progressive disease; PR, partial response; SD, stable disease.