Table 1.
The basic clinical characteristics of hypertensive patients with or without CCBs.
| Items | CCBs (unmatched; n = 1078) | Non-CCBs (unmatched; n = 371) | Statistics (F/Z/χ2) | P value | CCBs (matched; n = 359) | Non-CCBs (matched; n = 359) | Statistics (F/Z/χ2) | P value |
| General condition | ||||||||
| Age, years | 66 (59, 73) | 65 (57, 72) | −1.88∗ | 0.0596 | 65 (57, 71) | 65 (57, 72) | −0.03∗ | 0.9756 |
| Male | 504 (46.75) | 199 (53.64) | 5.24† | 0.0221 | 182 (50.70) | 188 (52.37) | 0.18† | 0.6541 |
| Temperature, degree centigrade | 36.5 (36.3, 36.7) | 36.5 (36.3, 36.7) | 0.27∗ | 0.7869 | 36.5 (36.3, 36.7) | 36.5 (36.3, 36.7) | −0.38∗ | 0.7023 |
| Respiratory rate, breaths per min | 20.0 (19.0, 20.0) | 20.0 (19.0, 20.0) | 0.22∗ | 0.8229 | 20.0 (19.0, 20.0) | 20.0 (19.0, 20.0) | 0.02∗ | 0.9833 |
| Pulse rate, per min | 84.0 (78.0, 94.0) | 85.0 (78.0, 96.0) | 0.88∗ | 0.3789 | 85.0 (78.0, 95.0) | 85.0 (78.0, 96.0) | 0.35∗ | 0.7231 |
| Disease severity | 0.97† | 0.3253 | 0.28† | 0.5983 | ||||
| Mild type | 34 (3.15) | 8 (2.16) | – | – | 10 (2.79) | 7 (1.95) | – | – |
| Ordinary type | 757 (70.22) | 262 (70.62) | – | – | 253 (70.47) | 257 (71.59) | – | – |
| Severe type | 254 (23.56) | 83 (22.37) | – | – | 86 (23.96) | 79 (22.01) | – | – |
| Critical type | 33 (3.06) | 18 (4.85) | – | – | 10 (2.79) | 16 (4.46) | – | – |
| Blood pressure, mmHg | ||||||||
| Systolic | 138.0 (126.0, 150.0) | 134.0 (124.0, 147.0) | −3.03∗ | 0.0025 | 135.0 (124.0, 145.0) | 134.0 (124.0, 147.0) | 0.04∗ | 0.9653 |
| Diastolic | 83.0 (76.0, 91.0) | 81.0 (74.0, 90.0) | −2.70∗ | 0.0069 | 80.0 (76.0, 90.0) | 82.0 (75.0, 90.0) | 0.18∗ | 0.8554 |
| Medical history | ||||||||
| Diabetes | 258 (23.93) | 98 (26.42) | 0.92† | 0.3382 | 103 (28.69) | 94 (26.18) | 0.57† | 0.4516 |
| Coronary heart disease | 136 (12.62) | 60 (16.17) | 2.98† | 0.0841 | 57 (15.88) | 55 (15.32) | 0.04† | 0.8370 |
| Kidney disease | 45 (4.17) | 23 (6.20) | 2.53† | 0.1117 | 20 (5.57) | 22 (6.13) | 0.10† | 0.7504 |
| COPD | 12 (1.11) | 12 (3.23) | 7.63† | 0.0058 | 10 (2.79) | 6 (1.67) | 1.02‡ | 0.3119 |
| Cancer | 10 (0.93) | 5 (1.35) | 0.15‡ | 0.6949 | 6 (1.67) | 4 (1.11) | 0.41‡ | 0.5242 |
| Anti-hypertensive treatment | ||||||||
| RAAS inhibitors | 193 (17.90) | 66 (17.79) | 0.00† | 0.9607 | 72 (20.06) | 65 (18.11) | 0.44† | 0.5062 |
| Beta-blockers | 298 (27.64) | 79 (21.29) | 5.78† | 0.0162 | 84 (23.40) | 78 (21.73) | 0.29† | 0.5922 |
| Diuretics | 149 (13.82) | 51 (13.75) | 0.00† | 0.9711 | 45 (12.53) | 47 (13.09) | 0.05† | 0.8233 |
| Others | 43 (3.99) | 18 (4.85) | 0.51† | 0.4753 | 12 (3.34) | 17 (4.74) | 0.90† | 0.3432 |
| Treatment | ||||||||
| Antiviral therapy | 645 (59.83) | 202 (54.45) | 3.30† | 0.0694 | 195 (54.32) | 196 (54.60) | 0.01† | 0.9403 |
| Antibacterial | 413 (38.31) | 140 (37.74) | 0.04† | 0.8439 | 129 (35.93) | 131 (36.49) | 0.02† | 0.8766 |
| Antifungal | 15 (1.39) | 5 (1.35) | 0.00‡ | 0.9503 | 4 (1.11) | 5 (1.39) | – | 0.7373 |
| Immunoglobulin | 220 (20.41) | 65 (17.52) | 1.46† | 0.2274 | 66 (18.38) | 62 (17.27) | 0.15† | 0.6965 |
| Glucocorticoid | 163 (15.12) | 53 (14.29) | 0.15† | 0.6969 | 56 (15.60) | 50 (13.93) | 0.40† | 0.5279 |
| Plasma | 1 (0.09) | 0 (0.00) | – | 0.5573 | 0 (0.00) | 0 (0.00) | – | – |
Data are presented as median (interquartile range) or n (%). ∗Z-statistics; †χ2-statistics; ‡F-statistics. CCBs: Calcium channel blockers; COPD: Chronic obstructive pulmonary disease; RAAS: Renin-angiotensin-aldosterone system.