Table 2.

Resting ventilatory parameters during normoxia (F_iO₂ 21%), hypoxia (F_iO₂ 10%), and hypercapnia (F_iCO₂ 7%) in HF after 6 weeks of exercise training (EX).

	HF + Sed (N = 5)	HF + EX-T (N = 5)	HF + EX-inT (N = 5)
Normoxia
VT (ml/100 g)	0.27 ± 0.01	0.24 ± 0.04	0.22 ± 0.04
Rf (breaths/min)	83.29 ± 5.18	87.89 ± 12.60	88.75 ± 9.96
Ve (mL/min 100 g)	22.62 ± 2.30	21.18 ± 0.83	19.59 ± 2.20
Ti (ms)	278.10 ± 53.21	276.90 ± 44.40	245.60 ± 15.46
Te (ms)	420.40 ± 23.48	420.60 ± 138.60	438.70 ± 73.37
Ttot (ms)	698.40 ± 54.26	697.40 ± 103.70	684.20 ± 67.07
PiF (ml/s)	9.69 ± 3.34	8.08 ± 2.32	8.38 ± 1.58
PeF (ml/s)	5.755 ± 1.56	5.33 ± 1.54	4.51 ± 0.95
Hypercapnia
VT(ml/100 g)	0.37 ± 0.08	0.32 ± 0.02	0.30 ± 0.03*
Rf (breaths/min)	201.8 ± 47.99	161.50 ± 16.68*	181.20 ± 29.69
Ve (mL/min 100 g)	74.74 ± 12.98	51.57 ± 3.98*	55.28 ± 4.07*
Ti (ms)	155.70 ± 23.01	180.10 ± 18.12*	204.40 ± 16.02*
Te (ms)	177.50 ± 55.20	197.70 ± 28.70	172.30 ± 15.67
Ttot (ms)	333.10 ± 97.63	377.90 ± 36.83	376.70 ± 28.69
PiF (ml/s)	18.66 ± 2.80	14.18 ± 1.63*	12.49 ± 2.78*
PeF (ml/s)	15.97 ± 3.09	12.57 ± 2.21*	10.03 ± 2.21*
Hypoxia
VT (ml/100 g)	0.32 ± 0.03	0.35 ± 0.04	0.27 ± 0.07+
Rf (breaths/min)	193.20 ± 21.31	174.20 ± 14.82	144.70 ± 16.06*+
Ve (mL/min 100 g)	61.62 ± 4.34	60.61 ± 4.05	40.86 ± 14.14*+
Ti (ms)	149.40 ± 13.37	151.30 ± 16.37	194.20 ± 19.57*
Te (ms)	170.50 ± 21.66	184.40 ± 17.90	227.80 ± 31.26*+
Ttot (ms)	320.00 ± 33.30	335.70 ± 21.52	422.00 ± 46.40*+
PiF (ml/s)	18.31 ± 2.82	17.33 ± 2.37	10.17 ± 2.41*+
PeF (ml/s)	17.5 ± 2.38	16.17 ± 2.23	11.69 ± 2.97*+

Values are expressed as mean ± SEM.

T: tolerant; inT: intolerant; VT: tidal volume; Rf: respiratory frequency; Ve: minute ventilation; Ti: inspiratory time; Te: expiratory time; Ttot: total respiratory time; PiF: peak inspiratory flow; and PeF: peak expiratory flow.

One-way ANOVA, Sidak post hoc analysis. *vs. HF + Sed, ⁺vs. HF + EX-T, p < 0.05.