Table 1.

writers, erasers and readers of Kcr.

	Family	Targets	Enzymes	Ref.
Writers	p300/CBP family	histone	p300, CBP	[15, 24]
		non-histone protein NPM1, DDX5	CBP	[9]
	MYST family	histone	MOF, yeast Esa1	[24]
			yeast Piccolo NuA4 complex	[29]
		non-histone protein NPM1	MOF	[9]
	GNAT family	histone	yeast Gcn5, Hat1	[26]
			yeast (ADA) complex	[29]
		non-histone protein NPM1, DDX5	PCAF	[9]
Erasers	HDAC I family	histone	HDAC3–NCoR1	[31]
			HDAC1, 2, 3, 8	[16]
			HDAC1, 2, 3	[14]
			HDAC1, 2	[32]
		non-histone protein NPM1	HDAC1, 3	[9]
	HDAC III family	histone	SIRT1, 2	[33]
			SIRT1, 2, 3	[34]
			SIRT1	[16]
Readers	YEATS domain family	histone	AF9, ENL, yeast Yaf9, Taf14	[37]
			YEATS2	[39]
			yeast Taf14	[26]
	DPF domain family		MOZ, DPF2	[38]
	bromodomain family		BRD9, TAF1 (but much weak than Kac)	[36]