Table 2.
Large-scale proteomic studies of Kcr.
| Organism | Biological sample analyzed | Number of Kcr sites | Number of Kcr proteins | Biological process or condition studied | Year | Refs |
|---|---|---|---|---|---|---|
| Human | ||||||
| H. sapiens | Hela | 28 | histone proteins | spermatogenesis | 2011 | [5] |
| H. sapiens | Hela | 558 | 453 non-histone proteins | Sodium crotonate treatment | 2017 | [6] |
| H. sapiens | A549 | 5096 | 1579 histone and non-histone proteins | SAHA treatment | 2017 | [8] |
| H. sapiens | H1299 | 2696 | 1024 non-histone proteins | NA (global Kcr survey) | 2017 | [9] |
| H. sapiens | HCT116 | 816 | 392 non-histone proteins | P300 knockout | 2018 | [25] |
| H. sapiens | Hela | 8 | histone proteins | CDYL knockout | 2017 | [58] |
| H. sapiens | Hela | 14311 | 3734 non-histone proteins | CDYL knockout | 2020 | [22] |
| H. sapiens | Peripheral blood | 1109 | 347 non-histone proteins | normal and maintenance hemodialysis patients | 2018 | [90] |
| H. sapiens | Peripheral blood | 770 | 353 non-histone proteins | normal and patients with immunoglobulin A nephropathy | 2020 | [91] |
| Mouse | ||||||
| M. musculus | MEFs | 24 | histone proteins | spermatogenesis | 2011 | [5] |
| M. musculus | Liver | 10034 | 2245 non-histone proteins | NA (global Kcr survey) | 2020 | [92] |
| Plant | ||||||
| O. sativa | Seedling leaves | 45 | histone proteins | starvation and submergence treatments | 2018 | [65] |
| O. sativa | Seedling leaves | 1265 | 690 non-histone proteins | NA (global Kcr survey) | 2018 | [63] |
| N. tabacum L. | Leaves | 2044 | 637 non- histone proteins | NA (global Kcr survey) | 2017 | [7] |
| A. hypogaea L. | Leaves | 6051 | 2508 non-histone proteins | NA (global Kcr survey) | 2021 | [64] |
| C. sinensis L. | Leaves | 2288 | 971 non-histone proteins | NH4+ deficiency/resupply | 2019 | [68] |
| C. papaya L. | Papaya fruit | 5995 | 2120 non-histone proteins | NA (global Kcr survey) | 2018 | [62] |
| D. grandiforum | Leaves | 2017 | 1199 non-histone proteins | Low temperature | 2021 | [67] |
| Microbiology | ||||||
| S. roseosporus | Cultured cells | 3944 | 1389 non-histone proteins | ΔprcB/A mutant | 2020 | [71] |
| C. albicans | Cultured cells | 5242 | 1584 non-histone proteins | NA (global Kcr survey) | 2021 | [73] |
| R. mucilaginosa | Cultured cells | 1691 | 629 non-histone proteins | patulin treatment | 2018 | [74] |
| S. roseosporus | Cultured cells | 3944 | 1389 non-histone proteins | proteasome-deficient ΔprcB/A | 2020 | [71] |
| B. cinerea | Cultured cells | 3967 | 1041 non-histone proteins | NA (global Kcr survey) | 2020 | [88] |
| Other species | ||||||
| D. rerio | Embryos | 557 | 218 non-histone proteins | NA (global Kcr survey) | 2018 | [89] |
| E. sinensis | Testis | 2799 | 908 histone and non-histone proteins | NA (global Kcr survey) | 2020 | [87] |
| T. gondii | T. gondii RH strain | 12152 | 2719 non-histone proteins | NA (global Kcr survey) | 2021 | [93] |
H. sapiens Homo sapiens, M. musculus Mus musculus, O. sativa Oryza sativa, N. tabacum L. Nicotiana tabacum L., C. sinensis L. Camellia sinensis L., C. papaya L. Carica papaya L., R. mucilaginosa Rhodotorula mucilaginosa, S. roseosporus Streptomyces roseosporus, B. cinerea Botrytis cinerea, D. rerio Danio rerio, E. sinensis Eriocheir sinensis, C. albicans Candida albicans, S. roseosporus Streptomyces roseosporus, D. grandiforum Dendranthema grandiforum, A. hypogaea L. Arachis hypogaea L., T. gondii Toxoplasma gondii, MEFs mouse embryonic. fibroblasts