Table 3.
Comparison of the catalytic activity of nano-ordered Melamine@TMG organocatalyst (1) versus some introduced catalysts for the synthesis of 5a.
| Entry | Catalyst (loading/solvent) | Temperature (°C) | Time (min) | Yield (%) | References |
|---|---|---|---|---|---|
| 1 | Melamine@TMG (2.5 mol%/EtOH) | 40 | 10 | 98 | This work |
| 2 | Nano-SiO2 (15 mol%/CH3CN) | r.t | 30 | 96 | 71 |
| 3 | p-Toluenesulfonic acid (15 mol%/CH3CN) | 50 | 25 | 95 | 73 |
| 4 | [Bmim]BF4 (15 mol%/Solvent-Free) | r.t | 11 | 92 | 77 |
| 5 | [C4(H-DABCO)2] [HSO4]4 (16 mg/Solvent-Free) | 90 | 12 | 91 | 67 |
| 6 | Molecular iodine (10 mol%/CH3CN) | Reflux | 10 | 81 | 76 |
| 7 | Anthranilic acid (30 mol%/EtOH) | 80 | 10 | 95 | 75 |