Skip to main content
. 2021 Jul 14;12(7):704. doi: 10.1038/s41419-021-03978-0

Fig. 5. STL enhances the cytotoxic effect of conventional chemotherapeutic drugs through suppression of FOXM1.

Fig. 5

a NSCLC and HGSOC cell lines were treated with indicated concentrations of carboplatin and STL alone or in combination for 48 h. b PEO1 cells with stable FOXM1 knockdown were treated with indicated concentrations of carboplatin and STL alone or in combination for 48 h. c Colorectal cancer cell lines were treated with indicated concentrations of 5-FU and STL alone or in combination for 24 h. d Prostate cancer and NSCLC cell lines were treated with indicated concentrations of docetaxel, paclitaxel, and STL alone or in combination for 24 h. In all cases, total protein samples were obtained from cells immediately after treatment and analyzed for FOXM1, cleaved caspase-3 and LC3 levels via immunoblotting, β-actin was used as an internal loading control.