Table 1.

Changes in expression of FOXM1-associated genes across a set of human cancer cell lines (LINCS data) caused by NPM1, AURKB, and MYC knockdown or treatment with candidate FOXM1-inhibiting agents.

GeneID	Gene symbol	Consensus gene expression changes (z-score values)
		NPM1 knockdown	AURKB knockdown	MYC knockdown	STL427944 treatment	Benzamil treatment
Direct target genes activated by FOXM1
332	BIRC5	−1.44	−1.43	−15.00	−6.05	−0.04
891	CCNB1	−3.21	−1.64	−7.87	−1.65	−1.30
9133	CCNB2	−2.55	−1.92	−16.66	−2.05	−0.90
983	CDK1	−3.32	−2.18	−7.66	−2.79	0.29
991	CDC20	−3.79	−3.26	−24.50	−9.48	−1.12
993	CDC25A	−1.19	−2.19	−7.96	−6.81	0.16
5347	PLK1	−1.39	−2.30	−10.60	−4.39	0.05
11065	UBE2C	−3.01	−1.27	−12.57	−4.05	−0.19