Table 1.

Experimental animal groups for evaluation of wound healing.

Groups	N	Treatment
		Mitomycin Ce	Spheroidsf	Nanosheetg
1. Untreated skin defecta	8	−	−	−
2. Untreated RUb	14	+	−	−
3. NS alone for RUc	8	+	−	+
4. ASCs spheroids NS for RUd	14	+	+	+

^aNo treatment after removal of skin and subcutaneous tissue.

^bNo treatment for mitomycin C-induced refractory ulcer.

^cTreatment by the nanosheet without ASC spheroids for mitomycin C-induced refractory ulcer.

^dTreatment by the nanosheet carrying ASC spheroids for mitomycin C-induced refractory ulcer.

^eTopical application of mitomycin C onto the wound.

^fTransplantation of 2 × 10² spheroids onto the wound.

^gApplication of a nanosheet onto the wound.