Table 2.

McNemar’s statistics of common DRB1 haplotypes and 2 bp del mutation.

Estimated haplotypes	Modela	nb	McNemar quadrants				b + cc	n	(b + c)/n	OR CI95			χ2	p value (exact)
			1;1	1;0	0;1	0;0
			a	b	c	d				OR	Lower	Upper
13:01	1 copy	58	11	23	13	95	36	142	0.25	1.77	0.90	3.5	2.25	0.067
13:01	1 or 2 two copy	62	11	14	26	91	40	142	0.28	1.86	1.00	3.6	3.03	0.042
13:01	2 copy	4	0	3	1	138	4	142	0.03	3.00	0.30	28.8	0.25	0.5
Haplogroup 13 (13:01, 13:02, and 13:03)
H/Y61T6	1 copy	62	11	27	13	91	40	142	0.28	2.07	1.10	4.0	4.23	0.022
H/Y61T	1 or 2 two copy	66	11	30	14	87	44	142	0.31	2.14	1.10	4.0	5.11	0.013
H/Y61T	2 copy	4	0	3	1	138	4	142	0.03	3.00	0.30	28.8	1.00	0.5
2 bp del	1 copy	64	10	31	13	88	44	142	0.31	2.39	1.20	4.6	6.57	0.006
2 bp del	1 or 2 two copy	69	11	33	14	84	47	142	0.33	2.36	1.30	4.4	6.89	0.005
2 bp del	2 copy	5	0	3	2	137	5	142	0.04	1.50	0.30	0.9	0.00	0.625
Lacking TMEM154 protective diplotypes
2 bp del	1 copy	43	4	26	9	53	35	92	0.38	2.89	1.40	6.2	7.31	0.004
2 bp del	1 or 2 two copy	47	4	29	10	49	39	92	0.42	2.90	1.40	6.0	8.31	0.002
2 bp del	2 copy	4	0	3	1	88	4	92	0.04	3.00	0.30	28.8	0.25	0.5

Table abbreviations: a, indicate the model that is “at least one copy” is dominant and “two copy” is recessive model; b, total number of ewes that are carriers of interested haplotype as one and/or two copies; c, sum of discordant pairs; OR, Odds ratio; χ², the McNemar’s test statistic with continuity correction; d, representing haplogroup 13 (*1301 and *1303).