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. 2021 Jul 14;12:4316. doi: 10.1038/s41467-021-24611-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a–f Top enriched organs, pathway categories, and cellular locations. Each plot shows the computed running sum (blue), running sums of random permutations (background), and the FDR adjusted P value. Exact p values were computed by the gene set enrichment analysis implementation of miEAA for each enrichment and FDR adjusted, separately for each database. g Pileup plot obtained from miRCarta for one of the overlapping miRNA candidates. The bars are colored according to the experiments the reads were contributed from. The expression is shown as reads per million mapped (RPMM). h Distribution of the read proportion supplied by each experiment that detected this miRNA.