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. 2021 Apr 8;46(9):1650–1657. doi: 10.1038/s41386-021-01003-8

Table 2.

Results from multilevel analyses examining the differential activation of threat neural circuitry ROIs across phases of fear conditioning and associations with symptom dimensions of general distress, fears and anhedonia-apprehension.

Parameter estimate Confidence interval p value
Fear acquisition (all CS+ vs. all CS−)
 (Intercept) 0.11 −0.04 0.26 0.143
 General Distress 0.00 −0.06, 0.07 0.947
 Fears −0.05 −0.12, 0.01 0.121
 Anhedonia-apprehension 0.04 −0.03, 0.10 0.244
Fear extinction (late CS+ vs. late CS−)
 (Intercept) −0.02 −0.17, 0.14 0.831
 General Distress −0.01 −0.08, 0.06 0.771
 Fears −0.02 −0.10, 0.06 0.576
 Anhedonia-apprehension 0.13 0.06, 0.20 0.001*
Extinction recall (early CS+ U vs. early CS+ E)
 (Intercept) 0.16 0.02, 0.30 0.030*
 General Distress 0.01 −0.05, 0.08 0.659
 Fears −0.06 −0.13, 0.01 0.103
 Anhedonia-apprehension 0.02 −0.04, 0.09 0.491

*p < 0.05.