Table 1.
Characteristics of included studies.
| Study | Year | Region | No. eyes | Mean age ± SD (yrs) | Gender (F/M) | Device (OCT) | Glaucoma types | Main outcome | Scan area (mm2 or mm3) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PPG | EG | OHT | PPG | EG | OHT | PPG | EG | OHT | ONH | Macular region | ||||||
| Wang et al. (44) | 2020 | China | 26 | 22 | 36.9 ± 11.1 | 41.4 ± 13.9 | 6/16 | 7/12 | RTVue | POAG | pRNFL, GCC | 6 × 6 | ||||
| Sarigül Sezenöz et al. (43) | 2020 | Turkey | 28 | 31 | 18 | 66.71 ± 11.33 | 68.20 ± 9.12 | 66.61 ± 10.44 | N/A | N/A | N/A | Heidelberg | Mixed | pRNFL, GCC, total retina thickness, G/T ratio | ||
| Lu et al. (42) | 2020 | China | 44 | 42 | 43 ± 11 | 46 ± 11 | 17/27 | 20/22 | RTVue | POAG | pRNFL, GCC | 4.5 × 4.5 | 6 × 6 | |||
| Hou et al. (41) | 2019 | USA | 68 | 162 | 68.4 ± 10.8 | 68.4 ± 8.6 | 30/25 | 60/61 | RTVue Spectralis | POAG | pRNFL, GCC | 3 × 3 | ||||
| Kim et al. (40) | 2017 | Korea | 26 | 26 | 52.08 ± 11.77 | 55.65 ± 13.36 | 16/10 | 16/10 | CirrusSpectralis | OAG | mRNFL, GCIPL, GCL, IPL | 6 × 6 | ||||
| Aydogan et al. (39) | 2017 | Turkey | 94 | 66 | 77 | 53.2 ± 11.1 | 59.4 ± 9.5 | 52.8 ± 8.2 | 57/37 | 36/30 | 62/15 | RTVue | Mixed | pRNFL, GCC, TR, OR | 3.45-mm circle | 7 × 7 |
| Akil et al. (38) | 2017 | USA | 20 | 20 | 63.13 ± 16.43 | 65.375 ± 5.2 | 10/10 | 8/12 | Cirrus | POAG | pRNFL | 3.4-mm circle | ||||
| Kumar et al. (37) | 2016 | India | 28 | 83 | 57.04 ± 2.78 | 61.2 ± 1.34 | N/A | N/A | RTVue | Mixed | pRNFL, GCC | 3.45-mm circle | 6 × 6 | |||
| Cennamo et al. (36) | 2016 | Italy | 66 | 41 | 64.86 ± 7.12 | 63.78 ± 11.70 | 30/36 | 25/16 | RTVue | OAG | pRNFL, GCC | 3.45-mm circle | 7 × 7 | |||
| Park et al. (35) | 2015 | Korea | 50 | 106 | 58.2 ± 13.7 | 56.0 ± 12.7 | 26/24 | 66/40 | Cirrus | Mixed | pRNFL, GCIPL, TNM ratio | 3.46-mm circle | 6 × 6 × 2 | |||
| Kim et al. (34) | 2015 | Korea | 79 | 83 | 54.6 ± 11.8 | 57.5 ± 11.6 | 40/39 | 43/40 | Cirrus | Mixed | pRNFL, GCIPL | Optic disc Cube 200 × 200 | Macular Cube 512 × 128 | |||
| Hwang et al. (33) | 2015 | Korea | 48 | 110 | 51.7 ± 13.8 | 51.6 ± 12.7 | N/A | N/A | Cirrus | Mixed | GCIPL | 6 × 6 | ||||
| Yamada et al. (32) | 2014 | Japan | 30 | 31 | 56.9 ± 14.7 | 61.8 ± 11.5 | 13/17 | 19/12 | Spectralis | Mixed | mRNFL, GCC, GCL, TR | 30 × 15 degreed macular area | ||||
| Sung et al. (31) | 2014 | Korea | 37 | 70 | 54.22 ± 12.70 | 53.97 ± 12.36 | 20/17 | 29/41 | Cirrus | Mixed | pRNFL, GCIPL | 3.46-mm circle | 14.13 mm2 elliptical annulus area | |||
| Kim et al. (30) | 2014 | Korea | 68 | 72 | 53.12 ± 10.69 | 56.83 ± 12.73 | N/A | N/A | 3D OCT-2000 | OAG | pRNFL, mRNFL, GCIPL, GCC | 3.46-mm circle | 6 × 6 | |||
| Kim et al. (29) | 2014 | Korea | 103 | 111 | 57.2 ± 11.8. | 56.8 ± 11.4 | 52/51 | 52/59 | Cirrus | OAG | pRNFL, GCIPL | 3.46-mm circle | Macular Cube 200 × 200 | |||
| Holló et al. (48) | 2014 | Hungary | 33 | 28 | 56.2 ± 12.1 | 50.7 ± 15.6 | N/A | N/A | RTVue | Mixed | pRNFL, GCC, total retina thickness, G/T ratio | 4-mm circle | ||||
| Arintawati et al. (28) | 2013 | Japan | 32 | 81 | 58.94 ± 12.15 | 60.16 ± 16.77 | 18/14 | 45/36 | RTVue | Mixed | pRNFL, GCC, FLV, GLV | 3.5-mm circle | 7 × 7 | |||
| Pomorska et al. (47) | 2012 | Poland | 33 | 27 | 61.0 ± 9.6 | 57.8 ± 11.2 | 17/16 | 18/9 | Sratus | Mixed | pRNFL | 3.4-mm circle | ||||
| Morooka et al. (27) | 2012 | Japan | 23 | 24 | 56.8 ± 9.4 | 51.9 ± 12.2 | 16/7 | 13/11 | RS3000 | Mixed | pRNFL, GCC | 3.45-mm circle | 9 × 9 | |||
| Horn et al. (26) | 2011 | Germany | 77 | 52 | 59.2 ± 10.0 | 60.8 ± 10.5 | 41/36 | 27/25 | Sepctralis | OAG | pRNFL | 3.4-mm circle | ||||
| Garas et al. (46) | 2011 | Hungary | 46 | 36 | 57.6 ± 11.8 | 51.5 ± 16.5 | N/A | N/A | RTVue | Mixed | pRNFL, GCC, FLV | 4-mm circle | ||||
| Taliantzis et al. (45) | 2009 | Greece | 42 | 54 | 58.1 ± 11.6 | 56.7 ± 13.2 | 20/22 | 25/29 | Stratus | Mixed | pRNFL | 3.4-mm circle | ||||
PPG, pre-perimetric glaucoma; EG, early perimetric glaucoma; OHT, ocular hypertension; OAG, open-angle glaucoma; POAG, primary open-angle glaucoma; Mixed, unclassified glaucoma or more than one types of glaucoma; pRNFL, peripapillary retinal nerve fiber layer; mRNFL, macular retinal nerve fiber layer; GCIPL, ganglion cell plus inner plexiform layer; GCL, ganglion cell layer; IPL, inner plexiform layer; GCC, ganglion cell complex; G/T ratio, macular GCC to total retinal thickness; TR, macular total retinal parameters; OR, macular outer retinal parameters; FLV, focal loss volume; GLV, global loss volume; TNM ratio, temporal to nasal macular GCIPL thickness ratio; F/M, female/male; ONH, optic nerve head.