Table 4.
Subgroup analysis of average and sectoral pRNFL thickness according to the type of OCT in patients with PPG and EG.
| Subgroup | No. | Heterogeneity | WMD (95% CI) | Overall effect | ||
|---|---|---|---|---|---|---|
| I2 | P | Z | P | |||
| RTVue SD-OCT | ||||||
| Average | 6 | 81% | <0.0001 | 6.96 (2.96, 10.95) | 3.42 | 0.0006 |
| Superior | 6 | 71% | 0.004 | 7.51 (2.98, 12.04) | 3.25 | 0.001 |
| Nasal | 2 | 0% | 1.00 | 8.70 (6.72, 10.68) | 8.60 | <0.00001 |
| Inferior | 6 | 77% | 0.0006 | 9.18 (4.13, 14.22) | 3.56 | 0.0004 |
| Temporal | 2 | 0% | 0.64 | 7.56 (4.64, 10.49) | 5.06 | <0.00001 |
| Cirrus SD-OCT | ||||||
| Average | 5 | 56% | 0.06 | 9.67 (7.09, 12.25) | 7.35 | <0.00001 |
| Superior | 4 | 14% | 0.32 | 12.04 (8.91, 15.17) | 7.53 | <0.00001 |
| Nasal | 3 | 93% | 0.00001 | 6.38 (-1.02, 13.78) | 1.69 | 0.09 |
| Inferior | 4 | 0% | 0.56 | 16.18 (13.24, 19.13) | 10.77 | <0.00001 |
| Temporal | 4 | 89% | <0.00001 | 7.74 (2.20, 13.29) | 2.74 | 0.006 |
PPG, pre-perimetric glaucoma; EG, early perimetric glaucoma; pRNFL, peripapillary retinal nerve fiber layer; OCT, optical coherence tomography; SD-OCT, spectral domain OCT; WMD, weighted mean difference; CI, confidence interval; I2, I-square heterogeneity statistic; Z, Z-statistic. The bold value refers to the study with a P value > 0.05.