Table 4.
ROM after TKA.a
| Cryoneurolysis group | Control group | Ratio estimate (95% CI) | P | |
|---|---|---|---|---|
| At discharge | ||||
| Number of patients with ROM data, n | 168 | 95 | – | – |
| Flexion degree, adjusted mean (95% CI) | 104 (102-106) | 91.5 (90-93) | 1.14 (1.11-1.16) | <.0001 |
| Flexion ≥90°, n (%) | 165 (98) | 78 (80) | 11.72 (3.56-38.55) | <.0001 |
| Extension degree, adjusted mean (95% CI) | 3.83 (3.37-4.35) | 4.57 (4.04-5.18) | 0.84 (0.74-0.94) | .0037 |
| Extension ≤5°, n (%) | 164 (97) | 77 (79) | 10.83 (3.68-31.92) | <.0001 |
| At week 2 | ||||
| Number of patients with ROM data, n | 158 | 91 | – | – |
| Flexion degree, adjusted mean (95% CI) | 107 (103-110) | 103 (100-107) | 1.03 (1.00-1.07) | .0501 |
| Flexion ≥90°, n (%) | 149 (88) | 84 (87) | 0.95 (0.42-2.16) | .9117 |
| Extension degree, adjusted mean (95% CI) | 4.44 (3.68-5.36) | 4.61 (3.92-5.44) | 0.96 (0.80-1.16) | .6855 |
| Extension ≤5°, n (%) | 164 (97) | 91 (94) | 1.73 (0.44-6.86) | .4332 |
| At week 6 | ||||
| Number of patients with ROM data, n | 160 | 94 | – | – |
| Flexion degree, adjusted mean (95% CI) | 124 (121-126) | 123 (121-126) | 1.00 (0.98-1.02) | .6787 |
| Flexion ≥90°, n (%) | 161 (95) | 93 (96) | 1.28 (0.34-4.88) | .7144 |
| Flexion ≥115°, n (%) | 145 (86) | 87 (90) | 0.61 (0.26-1.47) | .2712 |
| Extension degree, adjusted mean (95% CI) | 2.11 (1.61-2.77) | 4.14 (3.21-5.34) | 0.51 (0.38-0.68) | <.0001 |
| Extension ≤5°, n (%) | 160 (100) | 87 (93) | NAb | – |
| Extension ≤2.5°, n (%) | 141 (88) | 67 (71) | 2.61 (1.27-5.40) | .0094 |
NA, not applicable; ROM, range of motion.
a
Model adjusted for age, sex, ASA physical status class, BMI, and prior opioid exposure.
b
Ratio estimate could not be calculated because all patients in the cryoneurolysis group had an extension degree ≤5°.