Table 1.

Summary of our fives cases and comparison with similar cases.

	1st case	2nd case	3rd case	4th case	5th case	Richtmann et al. (1st case) [16]	Richtmann et al. (2nd case) [16]	Pulinx et al. [17]	Schwartz et al. [18]	Hosier et al. [14]
Date of SARS-Cov-2 infection	April 2020	September 2020	November 2020	December 2020	December 2020	NC	NC	NC	NC	March 2020
Maternal age	35	26	33	30	43	32	35	32	32	35
Mother BMI (beginning at of the pregnancy)	19,6	20.1	21	20.3	26.8	30.5	25.7	NC	NC	NC
Ethnicity	Caucasian	Caucasian	Caucasian	Caucasian	Caucasian	Caucasian	Caucasian	NC	NC	Asian American
Obstetrical background	G2P1	G1P0	G2P1	G1P0	G11P8	G1P0	G2P1	G2P1	NC	G3P1
Other background	Genital Herpes	None	None	None	Bypass surgery	None	None	NC	NC	None
Risk factors	None	None	None	None	Smoking (10 cigarettes a day before pregnancy)	None	None	Diabetes mellitus	NC	Psoriasis (without current symptoms) Gestational hypertension
Pregnancy follow up	Normal	Normal	Normal	Normal	IUGR at 26 GW	Normal	Normal	Normal	Normal	Normal
Clinical signs leading to SARS-Cov-2 RT-PCR	Fever	Fever	Fever	Ageusia and fever	Fever	Rhinorrhea, myalgia and fever	Fever, dry cough	Rhinitis and fever	None	Fever, cough, myalgia, nausea, anorexia, diarrhea
Delay between COVID PCR swab and onset of the Poor outcome	COVID day 6	COVID day 10	COVID day 10	COVID day 4	COVID day 28	COVID day 4	COVID day 6	COVID day 15	Unknown	COVID day 10
Delivery mode	C-section	Natural	Natural	Natural	C-section	Natural	Natural	Natural	NC	Dilatation and evacuation (Under general anesthesia)
Term (weeks)	26 + 5	34 + 5	30	22 + 4	26 + 5	28	21	24	39	22
Sex	Female	Female	Male	Male	Female	Female	Male	NC	Male	Unknown
Fetal weight (g)	680	2410	1210	465	630	1070	329	NC	NC	485
Fetal outcome	Neonatal intensive unit care	Fetal death	Fetal Death	Fetal death	Neonatal intensive care unit	Fetal death	Fetal death	Fetal death	Fetal death	Termination of pregnancy (Severe Pre-eclampsia)
Autopsy results	Not concerned	No abnormality	No abnormality	No abnormality	Not concerned	NP	No abnormality	NP	NP	No abnormality
Placental weight (g)	187 (<10th p+)	346 (<10thp+)	255 (<10th+)	105 (<10thp+)	196 (<10thp+)	NC	NC	NC	NC	NC
Ratio of fetal-placental weight ratio percentiles	3.63 (25-50thp+)	6.96 (50-75thp+)	4.74 (25-50thp+)	4.42 (>95thp+)	3.21 (10-25thp+)	NC	NC	NC	NC	NC
Placental histology	CHI	CHI	CHI	CHI	Focal CHI	CHI	CHI	CHI	CHI	CHI
	MPFD	MPFD	MPFD	MPFD	MPFD	MPFD	MPFD	MPFD	MPFD	MPFD
	LIT	LIT	LIT	LIT		VUE
SARS-Cov-2 RT-PCR on placenta (CT)	23	+ (38.7)	+ (27.59)	–	+ (30.5)	+ (NC)	NP	33	+ (NC)	+ (NC)
SARS-Cov-2 immunostaining	+	+	+	+	+	NP	NP	+	+	+