Table 1.
Reasons of COVID-19 infection and mortality after commonly used COVID-19 vaccinations.
| Name of vaccine/References | Manufacturer Company/organization/Institute of origin |
Type/Features of Vaccine | Reasons of COVID-19 infection and mortality | |
|---|---|---|---|---|
| 1 | AZD1222 (ChAdOx1) [13,14,15, WHO, CDC] |
Oxford/AstraZeneca COVID-19 vaccine University of Oxford, UK |
Chimpanzee adenoviral vector ChAdOx1, with the SARS-CoV-2 spike glycoprotein antigen. | 1) Vaccine escape 2) Ineffective against some Mutant strains 3) Very rare <1/10000 of VITT |
| 2 | BNT162b2 [29, CDC 37] |
Pfizer-BioNTech USA, Germany (Pfizer, Inc., and BioNTech) |
mRNA vaccine encoding SARS-CoV-2 spike glycoprotein. | 1) Vaccine escape 2) Ineffective against some Mutant strains 3) Myocarditis and pericarditis 4) Death in Frail, elderly population 5) Anaphylaxis may lead to death due to ingredient in mRNA Vaccine e.g. polyethylene glycol (11.1 cases per million doses administered after receipt of the first dose of the Pfizer-BioNTech vaccine) |
| 3 | mRNA-1273 [37] [CDC 37] |
ModernaTX, Inc USA |
mRNA vaccine encoding SARS-CoV-2 spike glycoprotein | 1) Myocarditis and Pericarditis 2) Anaphylaxis may lead to death due to ingredient in mRNA Vaccine e.g. polyethylene glycol (2.5 cases per million Moderna COVID-19 vaccine doses administered) |
| 4 | JNJ-78436735 [37] [9, CDC 37] |
Janssen Pharmaceuticals Companies of Johnson & Johnson, USA | Viral Vector- Adenovirus Ad26.COV2.S encoding SARS-CoV-2 spike glycoprotein | 1) Vaccine escape 2) May be ineffective against some Mutant strains 3) Anaphylaxis may lead to death due to ingredient in the J&J/Janssen COVID-19 vaccine (such as polysorbate) 4) Risk of blood clots with low platelets after vaccination, especially in younger Females |
| 5 | ChAdOx1 [8,10,38,39]. | Covishield, Serum Institute Pune, India |
Chimpanzee adenoviral vector ChAdOx1, with the SARS-CoV-2 spike glycoprotein antigen. | Like Oxford/AstraZeneca COVID-19 vaccine University of Oxford, UK |
| 6. | BBV152 [39] |
COVAXIN, Bharat Biotech/ICMR India |
Whole-virion inactivated SARS-CoV-2 vaccine | Not available |
WHO=World Health Organisation; CDC= Centre for Disease Prevention and Control; VITT= Vaccine-Induced Immune Thrombotic Thrombocytopenia; RNA = Ribo-nucleic acid; USA= United States of America; NA= Not available?.