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. 2021 Jul 1;11:656421. doi: 10.3389/fcimb.2021.656421

Table 3.

Aptamers developed for diagnosis and therapeutic applications in tuberculosis.

S. No. Aptamer Type Organism Target Reference
For Diagnosis
1. CE24 CE15 DNA M.tb H37Rv CE protein Tang et al., 2014
2. CSIR 2.11 DNA M.tb CE protein Rotherham et al., 2012
3. MPT64-A1 DNA M.tb MPT64 Zhu et al., 2012
4. G43 G78 RNA M.tb EsxG protein Ngubane et al., 2014
5. MA1 DNA M.tb Whole-bacterium Aimaiti et al., 2015
6. Aptamer 1 DNA M.tb Whole-bacterium Chen et al., 2007
7. Au-IDE/CFP10- ESAT6 DNA M.tb Whole-bacterium He et al., 2016
For therapeutic
8. NK2 DNA M.tb H37Rv Whole-bacterium Chen et al., 2007
9. ZXL1 DNA M.tb H37Rv ManLAM Pan et al., 2014
10. M. tb -Apt1
M. tb -Apt6
DNA M.tb Acetohydroxyacid synthase Baig et al., 2015
11. BM2 DNA BCG ManLAM Sun et al., 2016
12. T9 DNA M.tb Beijing strains ManLAM Tang et al., 2016
13. CD44-TA-SMP -- M.tb CD44 receptor Leonard et al., 2017