Figure EV2. Related to Fig 2. Comparison of Bax (α2–α5) dimer structures in bicelles (yellow) to crystal structures of Bax (α2–α5) (cyan) and Bak (α2–α5) (salmon) dimers.

• A
  Three‐dimensional structure superposition of the structure of Bax (α2–α5) in bicelles determined by NMR (yellow; PDB code: 6L8V) and the structure determined by crystallography in the absence of membranes (cyan; PDB code: 4BDU).The RMSD value between the superimposed protein backbones is 3.878 Å. Note that the residues from K123 to S126 form an extra α helical turn (orange) in the NMR structure.
• B
  Three‐dimensional structure superposition of the bicelle‐bound structure of Bax (α2–α5) (yellow; PDB code: 6L8V) and the Bak (α2–α5) dimer structure determined by crystallography in the absence of membranes (salmon; PDB code: 4U2V). The RMSD value between the superimposed protein backbones is 5.177 Å.