Figure EV4. Related to Fig 4. Pore‐forming activity of Bax mutants at low or high concentration.

• A–D
  The fluorescent dye release from mitochondrion‐mimic liposomes by 25 or 200 nM wt or mutant Bax in the presence or absence of 4 nM tBid as indicated was measured during a time course by fluorescence quenching. The fraction of dye release was normalized to that by detergent. The data shown were obtained from n = 3 independent replicates using the same preparations of the proteins and liposomes.

Source data are available online for this figure.