TABLE 3.
Biochemical parameters at diagnosis and at the last follow‐up visit
| Biochemical parameters | At diagnosis, % (n) | At last follow‐up, % (n) |
|---|---|---|
| ALP | N = 280 | N = 379 |
| ≤ULN | 21.8 (61) | 47.8 (181) |
| ULN < ALP ≤ 1.5xULN | 21.8 (61) | 26.9 (102) |
| 1.5xULN < ALP ≤ 3xULN | 30.7 (86) | 19.8 (75) |
| >3xULN | 25.7 (72) | 5.5 (21) |
| ALT | N = 253 | N = 349 |
| ≤ULN | 24.5 (62) | 68.8 (240) |
| >ULN | 75.5 (191) | 31.2 (109) |
| AST | N = 248 | N = 343 |
| ≤ULN | 23.8 (59) | 58.9 (202) |
| >ULN | 76.2 (189) | 41.1 (141) |
| GGT | N = 242 | N = 371 |
| ≤1.5xULN | 15.3 (37) | 49.3 (183) |
| >1.5xULN | 84.7 (205) | 50.7 (188) |
| Bilirubin | N = 228 | N = 363 |
| ≤ULN | 80.7 (184) | 80.7 (293) |
| >ULN | 19.3 (44) | 19.3 (70) |
Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma‐glutamyl transferase; ULN, upper limit of normal.