Table 8.

Relative gene expression differences between average BW piglets of sows fed diets with total ITM and Replace¹

Function	Response	Gene	ITM	Replace	Contrast statistic2	P-value	FDR
Barrier function	Mucin 13	MUC13	0.75	0.95	4.597	0.046	0.424
	Zonula occludens 1	ZO1	1.14	1.39	3.368	0.083	0.424
Immune response	Guanylate binding protein 1	GBP1	0.06	0.51	4.567	0.047	0.424
	Heat shock protein 4	HSPA4	2.02	2.70	4.475	0.049	0.424
	Interleukin 1 beta	IL-1β	2.39	18.23	4.140	0.058	0.424
	Interleukin 8	IL8	1.74	3.59	3.463	0.079	0.424
	Interleukin 6	IL6	1.43	2.64	3.406	0.082	0.424
	Transforming growth factor beta 1	TGF-β1	1.58	2.43	4.554	0.047	0.424
Stress enzyme	Hydroxysteroid (11-beta) dehydrogenase 1	HSD11B1	1.92	2.92	6.058	0.024	0.424

¹Data are means of 10 newborn piglets per sow experimental diet. Only significant gene expression differences are presented (P < 0.10). Gene expression values are presented as ratios of cycle relative threshold value for each gene normalized to that of the reference sample.

²Contrast statistic expresses the variability comparison between the experimental diet and the residual variability within diets.