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. 2021 Jun 23;8(2):291–299. doi: 10.5455/javar.2021.h514

Table 5. AUC, cut-off points, sensitivity%, specificity%, LR, PPV, NPV, and accuracy rate for MMP-2, MMP-9, and TAC in EG compared to CG and in TGs compared to EG.

MMP-2 (ng/ml) MMP-9 (ng/ml) TAC (Mm/l)
EG TGs EG TGs EG TGs
AUC 1 1 1 1 1 1
Cut-off points 15.9 64.97 23.70 71.44 1.06 0.78
Sensitivity % 100% 100% 100% 100% 100% 100%
Specificity % 70% 65% 75% 80% 95% 95%
LR 3.33 2.86 4 5 20 20
PPV 86.96% 41.67% 88.89% 83.33% 97.5% 95.24%
NPV 100% 100% 100% 100% 100% 100%
Accuracy rate 90% 72% 91.67% 90% 98.33% 97.5%

AUC = 0.86–1 (with satisfactory sensitivity and specificity: excellent marker)

LR < 5: low; = 5–10: moderate; >10: high.