Table 4.
Summary of sensitivity and specificity of cervical cancer screening methods for detecting CIN2-3.
| Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | References |
|---|---|---|
| CYTOLOGY | ||
| 65.9 (54.9–75.3)* | 96.3 (94.7–97.4) | (85) |
| 75.5 (66.6–82.7)† | 91.9 (88.4–94.3) | (86) |
| HPV DNA TESTING | ||
| 88.1(81.4–92.7) | 83.7 (74.9–89.8) | (87) |
| 88.3 (73.1–95.5) | 73.9 (50.7–88.7) | (87) |
| 94.0 (89.0–97.0) | 88.0 (84.0–92.0) | (88) |
| VISUAL INSPECTION WITH ACETIC ACID | ||
| 79.2 | 84.7 | (89) |
| 82.4 (76.3–87.3) | 87.4 (77.1–93.4) | (90) |
| 78.0 (73.0–83.0) | 88.0 (85.0–91.0) | (91) |
| 69.0 (54.0–81.0) | 87.0 (79.0–92.0) | (91) |
| VISUAL INSPECTION WITH ACETIC ACID AND LUGOL'S IODINE | ||
| 89.0 | 85.0 | (90) |
| 90.0 (85.0–94.0) | 83.0 (79.0–86.0) | (91) |
*
Conventional Pap.
†
Liquid-based cytology.
Endpoints are all CIN2-3, reference standard = colposcopy with or without biopsy.