Table 5.

Summary of efficacy of LEEP, cold knife conization, cryotherapy, and thermal ablation.

Method	Endpoint	Pooled cure proportions (%, 95% CI)	References
LEEP
	CIN2-3 negative after 12 months	94.7 (96.3–93.1)	(122)
	HSIL negative after 12 months follow up	92.0 (N/A)	(123)
COLD KNIFE CONIZATION
	CIN2-3 negative after 12 months	98.6 (99.2–98.0)	(124)
CRYOTHERAPY
	CIN2-3 negative after 6 months in LMICs	82.6 (77.4–87.3)	(125)
	CIN2-3 negative at follow up (duration unspecified)	86.0 (83.0–89.0)	(126)
	CIN2-3 negative after 12 months	94.7 (96.1–93.2)	(124)
	HSIL negative after 12 months follow up	80.9 (N/A)	(123)
THERMAL ABLATION
	CIN2-3 negative after 6+ months	91.6 (88.2–94.5)	(125)
	CIN2-3 negative after 6+ months (LMICs only)	82.4 (75.4–88.6)	(125)
	CIN2-3 negative after 4–6 months	93.6 (90.8–96.0)	(127)