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. 2021 Jul 14;11(7):e052755. doi: 10.1136/bmjopen-2021-052755

Table 3.

30-day hospital readmissions for different classes of drugs based on ATC (N=13 802)

Drug class 30-day readmission with no drugs in this class (%) 30-day readmission with drugs in this class (%) P value
First level, anatomical main group
 Blood and blood-forming organ drugs (B) 7.1 8.0 NS
 Dermatologicals (D) 7.7 9.4 NS
 Genitourinary system and sex hormones (G) 7.7 8.3 NS
 Systemic hormonal preparations, excluding sex hormones and insulins (H) 7.4 9.5 ***
 Anti-infectives for systemic use (J) 8.0 7.2 NS
 Antineoplastic and immunomodulating agents (L) 7.6 12.6 ***
 Drugs for the musculoskeletal system (M) 8.0 6.5 *
 Antiparasitic products, insecticides and repellents (P) 7.8 6.6 ***
 Respiratory system drugs (R) 7.4 9.9 ***
 Sensory organ drugs (S) 7.8 8.4 NS
Second level, therapeutic subgroup
 Stomatological preparations (A01) 7.8 12.2 NS
 Drugs for acid-related disorders (A02) 7.0 8.5 ***
 Drugs for functional gastrointestinal disorders (A03) 7.4 13.4 ***
 Antiemetics and antinauseants (A04) 7.7 27.7 ***
 Bile and liver therapy drugs (A05) 7.8 14.3 NS
 Drugs for constipation (A06) 7.3 10.8 ***
 Antidiarrhoeals, intestinal anti-inflammatory/anti-infective agents (A07) 7.7 12.9 ***
 Digestives, including enzymes (A09) 7.8 10.0 NS
 Drugs used in diabetes (A10) 7.4 9.5 ***
 Vitamins (A11) 7.5 9.9 ***
 Mineral supplements (A12) 7.4 8.8 **
 Other alimentary tract and metabolism products (A16) 7.8 6.3 NS
 Cardiac therapy (C01) 7.6 8.9 NS
 Antihypertensives (C02) 7.7 14.1 ***
 Diuretics (C03) 7.2 9.8 ***
 Peripheral vasodilators (C04) 7.8 15.2 NS
 Vasoprotective drugs (C05) 7.8 9.8 NS
 Beta-blocking agents (C07) 7.1 8.6 ***
 Calcium channel blockers (C08) 7.7 8.6 NS
 Agents acting on the renin–angiotensin system (C09) 8.7 7.1 ***
 Lipid-modifying agents (C10) 8.3 7.1 **
 Anaesthetics (N01) 7.8 18.8 *
 Analgesics (N02) 7.8 7.8 NS
 Antiepileptics (N03) 7.7 9.0 NS
 Drugs for Parkinson’s disease (N04) 7.8 6.9 NS
 Psycholeptics (N05) 6.8 9.3 ***
 Psychoanaleptics (N06) 7.8 7.7 NS
 Other nervous system drugs (N07) 7.9 5.1 NS

*P<0.05, **P<0.01, ***P<0.001.

ATC, Anatomical Therapeutic Chemical Classification System; NS, non-significant.