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. 2021 Jul 14;6(7):e006014. doi: 10.1136/bmjgh-2021-006014

Table 2.

Estimates of acute lower respiratory infections (ALRI) in-hospital case-fatality ratios (hCFRs, %) and in-hospital mortality in children and adolescents aged 5–19 years by UNICEF region and World Bank income region

Region No. of studies hCFR (%) In-hospital mortality
By UNICEF region†
Asia-Pacific 5 0.6 (0.2–2.5) 21 000 (5300–87 400)
Sub-Saharan Africa 6 2.1 (0.8–5.6) 19 300 (7200–49 100)
Eastern Europe and Central Asia 0
High-income countries 8 0.3 (0.1–0.5) 700 (300–1200)
Latin America and Caribbean 4 1.6 (0.4–5.8) 7500 (2100–26 300)
Middle East and North Africa 4 1.3 (0.7–2.3) 1100 (600–2200)
By World Bank income region
Low income and lower middle income 7 1.6 (0.7–4.1) 51 100 (18 300–126 600)
Upper middle income 8 1.6 (0.6–4.2) 32 500 (11 900–90 400)
High income 12 0.4 (0.2–0.6) 1000 (600–1800)
Global‡ 87 900 (40 300–180 600)

*hCFR estimates were from meta-analyses. In-hospital mortality were estimated by combining hCFR estimates and the ALRI hospital admissions for 5–19 years.

†Asia-Pacific: the region of South Asia and the region of East Asia and the Pacific were combined due to the insufficient data. Sub-Saharan Africa: the region of Eastern and Southern Africa and the region of West and Central Africa were combined due to insufficient data.

‡Global estimates were calculated as the sum of estimates by World Bank income region. The point value of the global estimate was slightly different from the sum of the point estimates by region due to the substantial uncertainties in the estimates across regions.