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. 2021 Jul 1;12:614773. doi: 10.3389/fimmu.2021.614773

Figure 1.

Figure 1

Differential expression of the checkpoint molecules HLA-G, PD-1, CTLA-4 and their receptors in the various types of human tumors (ONCOMINE database). Graph shows the number of datasets with a statistically mRNA overexpression, based on the cut-off value of P < 0.05, fold change >1.5, and gene rank in the top 10% in the ONCOMINE database. Red represents over-expression, blue represents down-expression, and white represents no difference in tumors vs. normal adjacent tissues.