Fig.1.

Association of Lag-3 and Lag-4 with DAS28 and HAQ-D1 (Impact on disease outcome) Pearson correlation was used to correlate lag-3 and lag-4 with HAQ-D1. Significant correlation between lag 3 (diagnostic delay) and DAS28 was found (r=0.2, p=0.02) (Fig. a) as well as between lag3 and HAQ (r=0.2, p= 0.003), (Fig. b) Similarly significant correlation between leg 4 (therapeutic delay) and DAS28 (r=0.2, p=0.03) (Fig. c) as well as between lag4 and HAQ (r=0.3, P=0.001) was found (Fig. d).