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Brain MRI of patient 3 at the ages of 1 year and 9 months old (A,B) and 3 years and 8 month old (C,D). MRI demonstrated bilateral lesions in the brain stem (red arrowheads), thalamus (white arrowheads), and dentate body of cerebellum (yellow arrowheads), with diffusion limitation in diffusion weighted image. There is no significant improvement during the follow-up period.
