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(A) Guanosine oxidation by the reactive oxygen species. The oxidation products, 8-oxo-G (8-oxoguanosine), Gh (guanidinohydantoin), and FapyG (2,6-diamino-4-hydroxy-5-formamidopyrimidine) and the change in molecular mass (M) of guanosine in parenthesis are shown. (B) Adenosine oxidation by the reactive oxygen species. The oxidation products, 8-oxo-A (8-oxoadenosine), and FapyA (4,6-diamino-5-formamidopyrimidine) are shown. These schemes are adopted from Cadet et al. (2016).
