Table 3.
Multivariate logistic regression analysis adjusted for age and gender.
| Gene | SNPs | Genetic Model | Genotype | Group 2 | Combined | |||
|---|---|---|---|---|---|---|---|---|
| P | OR (95%CI) | P | OR (95%CI) | |||||
| CPED1, WNT16 | rs2707520 | Dominant | CC | 1.00 | 1.00 | |||
| CA+AA | 0.067 | 0.698 (0.475-1.026) | 1.39E-03 | 0.566 (0.400-0.803) | ||||
| rs2707521 | Dominant | CC | 1.00 | 1.00 | ||||
| CT+TT | 0.089 | 0.717 (0.488-1.052) | 0.002 | 0.580 (0.410-0.821) | ||||
| VPS53 | rs61644407 | Dominant | AA | 1.00 | 1.00 | |||
| AC+CC | 0.062 | 1.435 (0.982-2.096) | 1.42E-03 | 1.750 (1.241-2.468) | ||||
| WWOX | rs75559202 | Dominant | CC | 1.00 | 1.00 | |||
| CG+GG | 0.079 | 1.510 (0.953-2.390) | 0.004 | 1.846 (1.223-2.785) | ||||
| SERPINA4 | rs5510 | Recessive | CC+CT | 1.00 | 1.00 | |||
| TT | 0.007 | 0.289 (0.116-0.717) | 0.002 | 0.277 (0.121-0.635) | ||||
| KIDINS220 | rs1044280 | Recessive | CC+CA | 1.00 | 1.00 | |||
| AA | 0.556 | 0.720 (0.241-2.153) | 0.224 | 1.722 (0.716-4.140) | ||||
| AOAH | rs2228410 | Overdominant | CC+TT | 1.00 | 1.00 | |||
| CT | 0.024 | 0.650 (0.448-0.944) | 0.009 | 0.638 (0.455-0.896) | ||||
| IQGAP2 | rs2455230 | Dominant | GG | 1.00 | 1.00 | |||
| GC+CC | 0.008 | 0.577 (0.384-0.866) | 8.90E-04 | 0.535 (0.370-0.774) | ||||
| HCG22 | rs2523855 | Dominant | GG | 1.00 | 1.00 | |||
| GC+CC | 0.009 | 0.606 (0.415-0.884) | 0.157 | 0.781 (0.555-1.100) | ||||
| ZBTB46 | rs2281929 | Dominant | TT | 1.00 | 1.00 | |||
| TC+CC | 7.75E-05 | 0.466 (0.319-0.680) | 1.18E-06 | 0.423 (0.299-0.599) | ||||
SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval.