Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 6;24(3):637. doi: 10.3892/mmr.2021.12276

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zheng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Effect of LDHA on apoptosis of Ishikawa cells. (A) Representative graphs of apoptosis detected by flow cytometry. (B) A higher number of Ishikawa cells underwent apoptosis when LDHA was knocked down (sh-LDHA) compared with the control (sh-Con). (C) Western blot analysis of apoptosis-related proteins. (D) Histogram of BID, BAX, BIK, BIM, PUMA, P-BAD/BAD, C-caspase 3, total caspase 3 and LDHA protein expression in Ishikawa cells. Values are expressed as mean ± SD of three independent experiments. Student's t-test was used to compare two groups. *P<0.05, **P<0.01 and ***P<0.001. LDHA, lactate dehydrogenase A; C-, cleaved; sh-, short hairpin; Con-, control; P-, phosphorylated.