TABLE 1.

Clinical trials featuring dietary interventions to treat Glioblastoma multiforme.

Dietary intervention	Author group
Ketogenic Diet wherein ketosis is maintained by consuming a 60% medium chain triglyceride oil-based diet*	Nebeling et al., 1995
Restricted 4:1 (fat: carbohydrate + protein) ketogenic diet that delivered roughly 600 kcal/day	Zuccoli et al., 2010
Calorie Restricted Ketogenic Diet (CRKD) with fasting during and after concurrent radiotherapy	Rieger et al., 2014
Ketogenic Diet with < 30 g Carbohydrates Daily	Jameson, 2014
Ketogenic diet with concurrent radiotherapy and temozolomide chemotherapy	Woolf et al., 2016
Ketogenic diet using a 3:1 ratio of grams of fat to grams of protein + grams of carbohydrates	Klein et al., 2020
Modified Atkins Diet (MAD): 65% of total calories from fat, 25% from protein, and 10% from carbohydrates	Strowd et al., 2015
Modified Ketogenic Diet (MKD): 70% of total calories come from dietary fat, carbohydrate limited to 20 g/day	Martin-McGill et al., 2018
KD vs. control with intranasal administration of perillyll alcohol	Guimarães Santos et al., 2018

*Trial targeted malignant astrocytoma rather than glioblastoma.