Table 4.

Comparison of renal histopathological data in patients with and without C4d deposition in different renal compartments.

	Glomeruli			Arteriole			PTC		TBM
	0/1+ 43pt	2+/3+ 282pt	P	Negative 223pt	Positive 102pt	P	Negative 215pt	Positive 110pt	P	Negative 183pt	Positive 142pt	P
AI score	9 (5-13)	7 (3-11)	0.102	7 (3-11)	8 (5-12)	0.023	7 (3-11)	9 (5-12)	0.011	5 (2-10)	9 (6-12)	<0.001
Endocapillary hypercellularity	3 (2-3)	2 (1-3)	0.243	2 (1-3)	3 (2-3)	0.067	2 (1-3)	3 (1-3)	0.184	2 (1-3)	3 (2-3)	<0.001
Cellular crescents	0 (0-2)	0 (0-2)	0.238	0 (0-2)	2 (0-2)	0.003	0 (0-2)	2 (0-2)	0.041	0 (0-2)	2 (0-4)	<0.001
Karyorrhexis/fibrinoid necrosis	2 (0-2)	0 (0-2)	0.021	0 (0-2)	0.5 (0-2)	0.311	0 (0-2)	2 (0-2)	0.037	0 (0-2)	2 (0-2)	0.014
Subendothelial hyaline deposits	1 (0-3)	1 (0-2)	0.078	1 (0-2)	1 (0-2)	0.631	1 (0-2)	1 (1-2)	0.040	1 (0-2)	1 (0-2)	0.037
Interstitial inflammatory cell infiltration	1 (1-2)	1 (1-1.25)	0.142	1 (1-1)	1 (1-2)	0.014	1 (1-1)	1 (1-2)	0.003	1 (1-1)	1 (1-2)	<0.001
Glomerular leukocyte infiltration	1 (1-1)	1 (0-1)	0.064	1 (0-1)	1 (0-1)	0.374	1 (0-1)	1 (0-1)	0.330	1 (0-1)	1 (0-1)	0.004
CI score	2 (2-3)	2 (2-4)	0.563	2 (1-3)	3 (2-4)	0.001	2 (1-3)	3 (2-4)	<0.001	2 (1-3)	3 (2-4)	<0.001
Glomerular sclerosis	0 (0-1)	0 (0-1)	0.041	0 (0-1)	0 (0-1)	0.022	0 (0-1)	0 (0-1)	0.019	0 (0-1)	0 (0-1)	0.134
Fibrous crescents	0 (0-0)	0 (0-0)	0.778	0 (0-0)	0 (0-0)	0.541	0 (0-0)	0 (0-0)	0.101	0 (0-0)	0 (0-0)	0.007
Tubular atrophy	1 (1-1)	1 (1-1)	0.637	1 (1-1)	1 (1-2)	<0.001	1 (1-1)	1 (1-2)	<0.001	1 (1-1)	1 (1-2)	<0.001
Interstitial fibrosis	1 (0-1)	1 (1-1)	0.685	1 (0-1)	1 (1-1)	<0.001	1 (0-1)	1 (1-1)	0.003	1 (0-1)	1 (1-1)	<0.001

Pt, patients; PTC, peritubular capillary; TMB, tubular basement membrane; AI, activity indices; CI, chronicity indices. Data were presented as median (interquartile range) in the table.