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. 2021 Jul 1;11:651671. doi: 10.3389/fonc.2021.651671

Table 1.

Demographic and clinicopathological features of patients receiving adjuvant chemotherapy and adjuvant chemoradiotherapy.

Variable Adjuvant Chemotherapy (n = 5,454) Adjuvant Chemoradiotherapy (n = 4,643) P Value
Age <0.001
 40–59 1,378 (25.3%) 1,442 (31%)
 60–79 3,637 (66.7%) 2,989 (64.4%)
 >80 439 (8%) 212 (4.6%)
Sex 0.007
 Female 2,738 (50.2%) 2,206 (47.5%)
 Male 2,716 (49.8%) 2,437 (52.5%)
Race 0.162
 White 4,520 (82.9%) 3,817 (82.2%)
 Black 503 (9.2%) 478 (10.3%)
 Other 431 (7.9%) 348 (7.5%)
Primary Site 0.015
 Head 3,952 (72.5%) 3,476 (74.9%)
 Body/tail 1,009 (18.5%) 763 (16.4%)
 Other 493 (9%) 404 (8.7%)
Grade <0.001
 1 541 (10%) 432 (9.3%)
 2 2,522 (46.2%) 2,350 (50.6%)
 3 1,910 (35%) 1,552 (33.4%)
 4 65 (1.2%) 42 (0.9%)
 Unknown 416 (7.6%) 267 (5.8%)
Tumor Size 0.018
 ≤2 cm 929 (17%) 697 (15%)
 2–4 cm 3,156 (57.9%) 2,726 (58.7%)
 >4 cm 1,369 (25.1%) 1,220 (26.3%)
Stage <0.001
 I 610 (11.2%) 364 (7.8%)
 II 4,612 (84.6%) 4,061 (87.5%)
 III 232 (4.2%) 218 (4.7%)
T <0.001
 T1 344 (6.3%) 179 (3.9%)
 T2 670 (12.3%) 564 (12.1%)
 T3 4,208 (77.2%) 3,682 (79.3%)
 T4 232 (4.2%) 218 (4.7%)
Nodal status <0.001
 N0 1,877 (34.4%) 1,402 (30.2%)
 N1 3,577 (65.6%) 3,241 (69.8%)

CRT, chemoradiotherapy.