Table 2.

Univariate and multivariate analysis of overall survival rate.

Variable	Univariate			Multivariate
	HR	95% CI	P Value	HR	95% CI	P Value
Age			<0.001			<0.001
40–59	1			1
60–79	1.094	1.037–1.153	0.001	1.101	1.044–1.161	<0.001
>80	1.261	1.140–1.394	<0.001	1.271	1.148–1.408	<0.001
Sex						0.002
Female	1			1
Male	1.086	1.037–1.138	0.001	1.078	1.028–1.130
Race			0.031			0.109
White	1			1
Black	1.035	0.958–1.119	0.383	1.081	0.999–1.169	0.053
Other	0.894	0.815–0.980	0.016	0.970	0.884–1.064	0.516
Primary Site			<0.001			0.009
Head	1			1
Body/tail	0.866	0.812–0.923	<0.001	0.905	0.847–0.967	0.003
Other	0.935	0.860–1.016	0.114	0.943	0.866–1.026	0.172
Grade			<0.001			<0.001
1	1			1
2	1.375	1.259–1.502	<0.001	1.295	1.185–1.415	<0.001
3	1.833	1.675–2.006	<0.001	1.660	1.516–1.818	<0.001
4	1.498	1.172–1.914	0.001	1.505	1.177–1.923	0.001
Unknown	1.232	1.086–1.398	0.001	1.232	1.085–1.399	0.001
Tumor Size			<0.001			<0.001
≤2 cm	1			1
2–4 cm	1.421	1.325–1.524	<0.001	1.246	1.150–1.350	<0.001
>4 cm	1.675	1.550–1.809	<0.001	1.470	1.347–1.606	<0.001
Stage			<0.001			<0.001
I	1			1
II	2.062	1.882–2.258	<0.001	1.269	1.111–1.451	<0.001
III	3.204	2.796–3.671	<0.001	2.390	1.981–2.884	<0.001
T			<0.001			0.027
T1	1			1
T2	1.540	1.340–1.769	<0.001	1.064	0.899–1.239	0.445
T3	2.091	1.847–2.368	<0.001	1.180	1.000–1.371	0.040
T4	3.224	2.478–3.784	<0.001	2.390	1.981–2.884	<0.001
Nodal status						<0.001
Negative	1			1
Positive	1.661	1.576–1.750	<0.001	1.441	1.358–1.530
Adjuvant therapy			0.124			0.003
Chemotherapy	1			1
Chemoradiotherapy	0.964	0.920–1.010		0.931	0.888–0.976

CI, confidence interval.