Table: III.
Most frequent Non-haematological toxicities (>10%)
| Adverse event | All grades* N=33 | Grade 1 N=33 | Grade 2 N=33 | Grade 3 N=33 |
|---|---|---|---|---|
| Gastrointestinal | 22 (67%) | 15 (45%) | 11 (33%) | 4 (12%) |
| Pleural effusion | 17 (52%) | 5 (15%) | 10 (30%) | 4 (12%) |
| Fatigue | 16 (48%) | 11 (33%) | 6 (18%) | - |
| Oedema | 9 (27%) | 6 (18%) | 4 (12%) | - |
| Myalgia | 9 (27%) | 3 (9%) | 7 (21%) | - |
| Rash | 8 (24%) | 6 (18%) | 3 (9%) | 1 (3%) |
| Fever | 7 (21%) | 5 (15%) | 2 (6%) | - |
| Shortness of breath | 7 (21%) | 3 (9%) | 3 (9%) | 3 (9%) |
| Anorexia | 6 (18%) | 1 (3%) | 5 (15%) | - |
| Headache | 6 (18%) | 5 (15%) | 1 (3%) | - |
| Infection | 6 (18%) | 2 (6%) | 6 (18%) | - |
| Cardiovascular | 5 (15%) | 4 (12%) | 1 (3%) | 2 (6%) |
| Neuropathy | 5 (15%) | 4 (12%) | 1 (3%) | - |
| Chills | 4 (12%) | 3 (9%) | 1 (3%) | - |
| Electrolyte abnormalities | 4 (12%) | 4 (12%) | - | - |
| Pericardial effusion | 4 (12%) | 4 (12%) | - | - |
*
If a patient had more than one event from Grade1–3, only one was counted in the percentage of all grades.