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. Author manuscript; available in PMC: 2021 Jul 15.
Published in final edited form as: Curr Biol. 2021 Jan 7;31(6):1268–1276.e6. doi: 10.1016/j.cub.2020.12.018

Figure 2. Cdc9 overexpression interferes with both Exo1-dependent and Exo1-independent MMR pathways.

Figure 2.

(A and B) Mutation rate analysis using the lys2-10A frameshift reversion reporter in the indicated yeast genetic backgrounds. Bars correspond to the median rate, with error bars representing the 95% confidence interval. Numbers on top of the bars indicate fold increase in mutation rate relative to WT. p values were calculated with the Mann-Whitney rank-sum test using SigmaPlot. ***p ≤ 0.001; n.s., not significant. See also Table S2 for additional mutation rate analysis using two alternative mutational reporters.