Table 3.

Associations of exposures with non-accidental and cause-specific mortality in two-exposure models ^{a, b}

Model	Exposure (IQR)	Non-accidental mortality	Circulatory disease mortality	Respiratory disease mortality	Lung cancer mortality	Neurodegenerative disease mortality
		HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
NO2 + NDVI 300 m	NO2 (8.3)	1.008 (1.003, 1.014)	1.007 (0.997, 1.017)	1.040 (1.022, 1.059)	1.035 (1.017, 1.055)	0.977 (0.960, 0.994)
	NDVI 300 m (0.14)	0.974 (0.971, 0.978)	0.989 (0.982, 0.996)	0.964 (0.952, 0.976)	0.934 (0.922, 0.946)	0.972 (0.960, 0.983)
PM2.5 + NDVI 300 m	PM2.5 (1.4)	1.007 (1.003, 1.010)	1.014 (1.007, 1.021)	1.051 (1.038, 1.064)	1.030 (1.017, 1.043)	1.004 (0.992, 1.015)
	NDVI 300 m (0.14)	0.973 (0.970, 0.977)	0.990 (0.983, 0.997)	0.964 (0.952, 0.975)	0.931 (0.920, 0.943)	0.978 (0.967, 0.989)
OPDTT + NDVI 300 m	OPDTT (0.3)	1.009 (1.005, 1.013)	1.009 (1.001, 1.017)	1.048 (1.033, 1.062)	1.025 (1.011, 1.039)	1.010 (0.997, 1.023)
	NDVI 300 m (0.14)	0.976 (0.972, 0.979)	0.991 (0.983, 0.998)	0.972 (0.959, 0.984)	0.934 (0.922, 0.947)	0.982 (0.970, 0.994)
road-traffic noise + NDVI 300 m	road-traffic noise (7.5)	1.000 (0.997, 1.003)	1.003 (0.997, 1.009)	0.996 (0.985, 1.007)	1.019 (1.008, 1.031)	0.967 (0.957, 0.977)
	NDVI 300 m (0.14)	0.972 (0.969, 0.976)	0.988 (0.981, 0.994)	0.953 (0.942, 0.965)	0.929 (0.918, 0.941)	0.970 (0.959, 0.981)
NO2 + TOP10NL 1000 m	NO2 (8.3)	1.005 (1.000, 1.011)	1.004 (0.993, 1.015)	1.050 (1.030, 1.071)	1.053 (1.033, 1.074)	0.979 (0.961, 0.997)
	TOP10NL 1000 m (0.31)	0.969 (0.964, 0.974)	0.983 (0.973, 0.993)	0.981 (0.963, 0.999)	0.964 (0.947, 0.982)	0.974 (0.958, 0.991)
PM2.5 + TOP10NL 1000 m	PM2.5 (1.4)	1.007 (1.003, 1.011)	1.013 (1.006, 1.020)	1.055 (1.041, 1.068)	1.037 (1.023, 1.050)	1.006 (0.994, 1.018)
	TOP10NL 1000 m (0.31)	0.968 (0.964, 0.973)	0.985 (0.976, 0.994)	0.974 (0.959, 0.99)	0.952 (0.936, 0.968)	0.985 (0.971, 1.001)
OPDTT + TOP10NL 1000 m	OPDTT (0.3)	1.009 (1.005, 1.013)	1.008 (1.000, 1.016)	1.058 (1.043, 1.073)	1.041 (1.026, 1.056)	1.017 (1.003, 1.030)
	TOP10NL 1000 m (0.31)	0.972 (0.966, 0.977)	0.986 (0.976, 0.996)	0.992 (0.974, 1.010)	0.964 (0.947, 0.982)	0.994 (0.977, 1.011)
road-traffic noise + TOP10NL 1000 m	road-traffic noise (7.5)	1.001 (0.998, 1.004)	1.003 (0.997, 1.009)	0.999 (0.988, 1.010)	1.025 (1.014, 1.036)	0.969 (0.959, 0.979)
	TOP10NL 1000 m (0.31)	0.967 (0.962, 0.971)	0.982 (0.973, 0.991)	0.959 (0.943, 0.974)	0.948 (0.932, 0.963)	0.975 (0.960, 0.990)
NO2 + road-traffic noise	NO2 (8.3)	1.023 (1.018, 1.029)	1.012 (1.001, 1.023)	1.072 (1.053, 1.093)	1.063 (1.043, 1.083)	1.016 (0.998, 1.034)
	road-traffic noise (7.5)	0.999 (0.995, 1.002)	1.002 (0.995, 1.008)	0.985 (0.974, 0.997)	1.014 (1.002, 1.027)	0.968 (0.957, 0.979)
PM2.5 + road-traffic noise	PM2.5 (1.4)	1.012 (1.008, 1.016)	1.016 (1.008, 1.023)	1.062 (1.049, 1.076)	1.039 (1.026, 1.053)	1.018 (1.006, 1.031)
	road-traffic noise (7.5)	1.002 (0.999, 1.006)	1.002 (0.996, 1.008)	0.991 (0.980, 1.002)	1.023 (1.012, 1.035)	0.968 (0.958, 0.978)
OPDTT + road-traffic noise	OPDTT (0.3)	1.020 (1.016, 1.023)	1.012 (1.005, 1.020)	1.063 (1.050, 1.077)	1.050 (1.036, 1.064)	1.028 (1.015, 1.040)
	road-traffic noise (7.5)	1.002 (0.998, 1.005)	1.003 (0.997, 1.009)	0.994 (0.983, 1.004)	1.023 (1.012, 1.035)	0.967 (0.958, 0.977)

^a Associations are expressed per IQR increase. We used models with age as underlying time scale, stratified by sex and adjusted for marital status, region of origin, standardized household income, PC4 composite SES, mean income neighborhood, unemployment neighborhood, percentage of immigrants neighborhood, mean income region, unemployment region and percentage of immigrants region

^b NO₂ and PM_2.5 were with the average of the national LUR, Europe-wide hybrid and national dispersion models. OP^DTT was estimated with a national LUR model